The Company
We are Alloy Therapeutics—a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN.

Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture.

This is an on-site and full-time position in Athens, GA. At Alloy, we have an ethos of “Mentorship-By-Apprenticeship” in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team!

The Team
Our Alloy-Athens team discovers biotherapeutic drugs using a novel high throughput antibody discovery platform. Located in Athens, GA, this small but dedicated team uses a variety of innovative methods for isolating antigen specific B cells to streamline the process of identifying therapeutic monoclonal antibodies within Alloy’s transgenic mouse platforms.

The Role
As a Protein Analytics Research Associate, you will collaborate with seasoned drug discovery experts to help identify potential life-saving therapeutics. This role will report to the Associate Scientist of Protein Analytics, and it requires an experienced, hard-working, creative and organized scientist with a positive attitude. With protein analytics and biochemistry as your focus, you will work in a matrixed environment where your diverse skills will be applied to support all teams in the discovery workflow.

How You’ll Drive Impact

Discover: Life-changing therapeutics through micro-scale, high-throughput antibody screening techniques.
Innovate: And refine cutting-edge analytical workflows using methods to assess protein functionality and interactions.
Organize: Experimental workflows, reagents, sample inventories, and data output with precision to ensure seamless lab operations.
Collaborate: Closely with cross-functional teams to deliver high-quality data that drives key decision-making processes.
Communicate: Experimental findings and provide actionable insights on novel protein properties to a matrixed team of researchers.

Principal Responsibilities

Conduct protein characterization assays, including concentration determination, aggregation analysis, and purity assessment.
Utilize high-throughput SPR and BLI to characterize protein-protein and protein-ligand interactions, generating high-quality kinetic and affinity data.
Prepare and execute ELISA and other plate-based assays to assess antigen-antibody interactions and other functional properties.
Maintain and operate analytical instruments to ensure consistent and accurate data production.
Design and execute experiments to troubleshoot and optimize workflows, ensuring reliability and efficiency in analytical processes.
Collaborate with other departments, including protein production, molecular biology, and immunology, to align on project goals and timelines.
Present experimental data and findings during team meetings, contributing to strategic decision-making processes.
Maintain laboratory organization, ensure compliance with safety protocols, and manage reagent inventories.
Stay current with emerging analytical techniques and technologies, incorporating them as appropriate to enhance laboratory capabilities.

Qualifications

BS/MS in Biochemistry or Protein Sciences, with 0-2 years of biotech/pharma experience
Industry experience in antibody drug discovery a plus
Hands-on experience with basic biochemical laboratory equipment and techniques (e.g., multichannel pipettors, Nanodrop, SDS-PAGE, CE-SDS, HPLC, FPLC, plate washers, plate readers, etc)
Experience working in a fast-paced and highly collaborative team environment
Excellent oral and written communication skills
Fluency with Microsoft Excel, Word, and Powerpoint
Experience with LIMS and/or ELN platforms, such as Benchling or similar
Experience with liquid handler protocols and programming a plus
Ability to work across various US and international time zones

Taking Care of Our People
We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you’re single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one.
Compensation

Competitive base and equity compensation commensurate with level of experience and independence
401(k) company match

Health & Family

Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered
Company-paid disability (STD, LTD) and life insurance
Paid parental leave
Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval)

Unique Perks

Unlimited PTO (paid time off) and flexible schedules
Annual stipend for continuing education with commitment to your career through individualized professional development plan
Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness

Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at recruiting@alloytx.com. We will make every effort to respond to your request for disability assistance as soon as possible.

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Alloy Therapeutics

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